返回首页
当前位置: > 医学论文 > 药 学 >

实验研究PI3K/Akt抑制剂联合顺铂治疗肺癌(3)

时间:2010-01-10 23:14来源:南粤论文中心 作者:吴秋歌 王静 蒋军广 点击:
2 Brognard J,Clark AS,Ni Y,et al.Akt/protein kinase B is constitutively active in non?small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation〔J〕.C
  

  2 Brognard J,Clark AS,Ni Y,et al.Akt/protein kinase B is constitutively active in non?small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation〔J〕.Cancer Res,2001;61(10):3986?97.

  3 段庚仙.非小细胞肺癌治疗现状〔J〕.肿瘤研究与临床,2003;15(4):756?78.

  4 Han JY,Chung YJ,Park SW,et al.The relationship between cisplatin?induced apoptosis and p53,bcl?2 and bax expression in human lung cancer cells〔J〕.Korean J Intern Med,1999;14(1):42?52.

  5 汤钊猷.现代肿瘤学〔M〕.第2版.上海:上海医科大学出版社,2000:461.

  6 Fulda S.Targeting inhibitor of apoptosis proteins(IAPs) for cancer therapy〔J〕.Anticancer Agents Med Chem,2008;8(5):533?9.

  7 Hannigan GE,Dedhar S.Protein kinase mediators of integrin signal transduction〔J〕.J Mol Med,1997;75(1):35?44.

  8 Alexia C,Bras M,Fallot G,et al.Pleiotropic effects of PI?3′ kinase/Akt signaling in human hepatoma cell proliferation and drug?induced apoptosis〔J〕.Ann N Y Acad Sci,2006;1090:1?17.

  9 Poh TW,Pervaiz S.LY294002 and LY303511 sensitize tumor cells to drug?induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3?kinase?Akt pathway〔J〕.Cancer Res,2005;65(14):6264?74.

  10 Page C,Lin HJ,Jin Y,et al.Overexpression of Akt/Akt can modulate chemotherapy?induced apoptosis〔J〕.Anticancer Res,2000;20(1):407?16.

  11 Gerber HP,Mc Murtrey A,Kowalski J,et al.Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′?kinase/Akt signal transduction pathway requirement for FIK?1/KDR activation〔J〕.J Biol Chem,1998;273(46):30336?43.

  12 Howells LM,Hudson EA,Manson MM.Inhibition of phosphatidylinositol 3?kinase/protein kinase B signaling is not sufficient to account for indole?3?carbinol?induced apoptosis in some breast and prostate tumor cells〔J〕.Clin Cancer Res,2005;11(23):8521?7.
 

(责任编辑:南粤论文中心)
顶一下
(0)
0%
踩一下
(0)
0%
------分隔线----------------------------
发表评论
请自觉遵守互联网相关的政策法规,严禁发布色情、暴力、反动的言论。
评价:
表情:
验证码:点击我更换图片
推荐内容